A CURA DI: Dott. Antonio Fusco

  • Longevità in salute

Longevità in salute

A CURA DI: Dott. Antonio Fusco

Infiammazione e stress ossidativo cellulare

1. G. Lippi. Lipidi e rischio cardiovascolare. Istituto di Chimica e Microscopia Clinica, Dipartimento di Scienze Morfologico-Biomediche, Università degli Studi di Verona, Verona. RIMeL / IJLaM 2005; 1
2. Anticorpi anti-lipoproteine a bassa densità ossidate: studi epidemiologici e potenziali applicazioni cliniche nella malattia cardiovascolare. Minerva Cardioangiologica 2007 Dicembre;55(6):821-37
3. Andreja Trpkovic et al. Oxidized low-density lipoprotein as a biomarker of cardiovascular diseases. Crit Rev Clin Lab Sci. 2015;52(2):70-85
4. Hiroyuki Itabe. Oxidized low-density lipoprotein as a biomarker of in vivo oxidative stress: from atherosclerosis to periodontitis. J. Clin. Biochem. Nutr. | July 2012 | vol. 51 | no. 1 | 1–8
5. Holvoet et al. Oxidized LDL and Malondialdehyde-Modified LDL in Patients With Acute Coronary Syndromes and Stable Coronary Artery Disease. Circulation. 1998; 98:1487-1494
6. Alexander N. Orekhov, Igor A. Sobenin. Modified lipoproteins as biomarkers of atherosclerosis. Frontiers In Bioscience, Landmark, 23, 1422-1444, March 1, 2018
7. Francesca Perrotti et al. Advances in Lipidomics for Cancer Biomarkers Discovery. Int. J. Mol. Sci. 2016, 17, 1992
8. Uffe Ravnskov et al. Lack of an association or an inverse association between low-densitylipoprotein cholesterol and mortality in the elderly: a systematic review. BMJ Open 2016.
9. Cole, T. et. al. (2013). Association of Apolipoprotein B and Nuclear Magnetic Resonance Spectroscopy–Derived LDL Particle Number with Outcomes in 25 Clinical Studies: Assessment by the AACC Lipoprotein and Vascular Diseases Division Working Group on Best Practices. Clinical Chemistry May 2013 vol. 59 no. 5 752-770
10. Carla Ferreri. Membrana cellulare e Lipidomica. Consiglio Nazionale delle Ricerche. Bologna
11. William S. Harris. Omega-3 Fatty Acids and Cardiovascular Disease: A Case for Omega-3 Index as a New Risk Factor. Pharmacol Res. 2007 March ; 55(3): 217–223
12. Clemens von Schacky and William S. Harris. Cardiovascular risk and the omega-3 index. Journal of Cardiovascular Medicine 2007, 8 (suppl 1):S46–S49
13. Sara Huerta-Yépez, Ana B. Tirado-Rodriguez, Oliver Hankinsona. Role of diets rich in omega-3 and omega-6 in the development of cancer. Bol Med Hosp Infant Mex. 2016;73(6):446---456
14. Ken D. Stark et al. Global survey of the omega-3 fatty acids, docosahexaenoic acid and eicosapentaenoic acid in the blood stream of healthy adults-Review. Progress in Lipid Research 63 (2016) 132–152
15. Barry Sears and Camillo Ricordi. Anti-Inflammatory Nutrition as a Pharmacological Approach to Treat Obesity. Journal of Obesity Volume 2011
16. Angela M Rizzo et al. A rapid method for determining arachidonic: eicosapentaenoic acid ratios in whole blood lipids: correlation with erythrocyte membrane ratios and validation in a large Italian population of various ages and pathologies. Lipids in Health and Disease 2010
17. Javier Amézaga et al. Altered Red Blood Cell Membrane Fatty Acid Profile in Cancer Patients. Nutrients 2018
Melinda Olliver et al. Erythrocyte omega-3 polyunsaturated fatty acid levels are associated with biomarkers of inflammation in older Australians. Journal of Nutrition & Intermediary Metabolism 5 (2016)
18. Jiahua Fan et al . Small dense LDL cholesterol is associated with metabolic syndrome traits independently of obesity and inflammation. Nutrition & Metabolism (2019) 16:7
19. Mi Na Lee et al Evaluation of the Analyti cal Performance of a Direct Quantitative Assay of Small Dense LDL. J Lab Med Qual Assur 2014;36:84 91
20. Philipp A Gerber, Dragana Nikolic, Manfredi Rizzo . Small, dense LDL: an update Curr Opin Cardiol. 2017 Jul;32(4):454 459
21. Lathan Liou, Stephen Kaptoge . Association of small, dense LDL cholesterol concentration and lipoprotein particle characteristics with coronary heart disease: A systematic review and meta analysis. PLOS ONE | November 9, 2020
22. Sanjiv Kumar Bansal, Sarita Agarwal, Mridul Kumar Daga. Advanced Atherogenic Index for the Assessment of Consolidated Lipid Risk in Premature Coronary Artery Disease Patients in India. Journal of Laboratory Physicians / Jul Dec 2016 / Vol 8 / Issue 2
23. Uffe Ravnskov et al. Lack of an association or an inverse a ssociation between low density lipoprotein cholesterol and mortality in the elderly: a systematic review. BMJ Open 2016
24. Uffe Ravnskov, Michel de Lorgeril, Malcolm Kendrick, David M. Diamond . Inborn Coagulation Factors are More Important Cardiovascular Risk Factors Than High LDL Cholesterol in Familial Hypercholesterolemia Medical Hypotheses 2018 Dec;121:60 63
25. Allan D. Sniderman et. al. Apolipoprotein B Particles and Cardiovascular Disease A Narrative Review . JAMA Cardiology, October 23, 2019 
26. Helena Vaverkova. LDL C or apoB as the best target for reduci ng coronary heart disease: should apoB be implemented into clinical practice? Clin. Lipidol. (2011) 6(1), 35 48
27. Cole, T. et. al. Association of Apolipoprotein B and Nuclear Magnetic Resonance Spectroscopy Derived LDL Particle Number with Outcomes in 25 Clinical Studies: Assessment by the AACC Lipoprotein and Vascular D iseases Division Working Group on Best Practices . Clinical Chemistry May 2013 vol. 59 no. 5 752 770
28. Andreja Trpkovic et al. Oxidized low density lipoprotein as a biomarker of cardiovascular diseases. Crit Rev Clin Lab Sci. 2015;52(2):70 85
29. Hiroyuki Itabe. Oxidized low density lipoprotein as a biomarker of in vivo oxidative stress: from atherosc lerosis to periodontitis . J. Clin. Biochem. Nutr. | July 2012 | vol. 51 | no. 1 | 1 8


Omega 3
 https://pubmed.ncbi.nlm.nih.gov/22062949/ https://pubmed.ncbi.nlm.nih.gov/22062949/ Nutraceutica https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5793269/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7823468/
  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5618938/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6463748/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3004578/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889804/ Metilazione 
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6084815/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4406451/ PQQ https://pubmed.ncbi.nlm.nih.gov/29185343/ http://manueladursi.it/pqq-pyrroloquinoline-chinone-e-la-biogenesi-mitocondriale/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6994848/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7003513/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5349805/
Radicali liberi
://www.ncbi.nlm.nih.gov/pmc/articles/PMC5349805/ì https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3664958/ì
 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7201853/ì https://italiano.mercola.com/sites/articles/archive/2020/09/04/protocollo-svizzero-per-covid-quercetina-e-zinco.aspx https://www.cnr.it/it/comunicato-stampa/9620/la-molecola-di-origine-naturale-che-inibisce-sars-cov-2 https://www.repubblica.it/salute/medicina-e-ricerca/2020/09/03/news/la_quercetina_contro-266129272/ https://www.panorama.it/news/salute/perche-la-quercetina-e-una-vera-promessa-anticovid 
 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1661741/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7801138/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC162286/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6061152/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363170/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3297890/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC140833/
https://pubmed.ncbi.nlm.nih.gov/19284182/ https://pubmed.ncbi.nlm.nih.gov/29211728/
  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7439809/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1042124/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC59787/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1160171/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7439809/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6480387/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5618634/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1967150/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1938199/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC124485/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5279831/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2443038/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC291304/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1068597/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1518055/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC296439/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1382992/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1820959/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4052624/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC35410/ https://www.ncbi.nlm.nih.gov/pmc/?term=Hiroyuki+2014 http://www.strettoweb.com/2020/09/coronavirus-andreoni-lattoferrina-proteina-permet te-liberarsi-molto-prima-covid/1058239/ https://www.onb.it/2020/07/28/lattoferrina-una-probabile-risposta-al-covid-lo-studio-diun-team-di-cl... 
Vitamina A e Lisozima
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5934683/ Choi S, Disilvio B, Fernstrom MH, Fernstrom JD. The chronic ingestion of diets containing different proteins produces marked variations in brain tryptophan levels and serotonin synthesis in the rat. Neurochem Res. 2011 Mar;36( 3): 559-65 Catassi, C.; Bonucci, A.; Coppa, G. V.; Carlucci, A.; Giorgi, P. L . Intestinal Permeability. Changes during the First Month: Effect of Natural versus Artificial Feeding. Journal of Pediatric Gastroenterology and Nutrition, November 1995, 21 ( 4): 383-386 Matsumoto e al. Gastroprotection by alpha-lactalbumin. Biosci. Biotechenol. Biochem. 65 ( 5) 1104- 1111 , 2001 Hushida S. et al. Effects of Bovine Alpha-lactalbumin on Gastric defense mechanism in naïve rats. Biosci. Biotechnol. Biochem. 67 ( 3), 577 -583, 2003 Pellegrini A, Thomas U, Bramaz N, Hunziker P, von Fellenberg R. Isolation and identification of three bactericidal domains in the bovine alpha-lactalbumin molecule. Biochim Biophys Acta. 1999 Feb 2;1426( 3): 439-48. Nieuwenhuizen AG, Hochstenbach-Waelen A, Veldhorst MA, Westerterp KR, Engelen MP, Brummer RJ, Deutz NE, Westerterp- Plantenga MS. Br J Nutr. 2009 Jun;101 ( 12): 1859-66. 05-08-2009   
Decadimento cognitivo, vitamina D e vitamina A
https://pubmed.ncbi.nlm.nih.gov/4050723/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2906676/ https://pubmed.ncbi.nlm.nih.gov/19940273/ https://onlinelibrary.wiley.com/doi/10.1002/eji.202048557 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6739868/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7668605/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7256687/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5793240/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6513642/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6494161/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4997277/
Vitamina K2 e MK7 
https://pubmed.ncbi.nlm.nih.gov/32995695/ https://pubmed.ncbi.nlm.nih.gov/25442537/ https://pubmed.ncbi.nlm.nih.gov/25228690/ https://pubmed.ncbi.nlm.nih.gov/9625097/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5812275/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6491307/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6747195/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357001/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429189/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6517256/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356938/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6235562/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874521/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4350006/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7761563/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5297730/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5297730/
https://pubmed.ncbi.nlm.nih.gov/31330843/ https://pubmed.ncbi.nlm.nih.gov/26197224/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4964502/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6836186/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412677/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5900571/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4058255/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4058255/
https://pubmed.ncbi.nlm.nih.gov/26232232/ https://pubmed.ncbi.nlm.nih.gov/27875732/ https://pubmed.ncbi.nlm.nih.gov/21369944/ https://pubmed.ncbi.nlm.nih.gov/24138806/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4935258/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4630419/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4420467/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6068203/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471701/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6266067/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5751192/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4942868/
Indole 3 carbinolo
https://pubmed.ncbi.nlm.nih.gov/23625645/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4945906/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2814317/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4180847/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4985490/
Omega3 e trigliceridi naturali
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6862261/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6516961/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6834330/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7230711/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5405443/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6439767/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6494196/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5477375/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3891543/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946223/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6431442/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627635/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6496684/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5412427/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121285/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5409706/
Interazioni tra Vitamina D e K7
Il ruolo della vitamina D nell'endocrinologia che controlla l'omeostasi del calcio. Mol. Cellula. Endocrinol. 2017 , 453 , 36–45. Fleet, JC
Gruppo di esperti scientifici EFSA sui prodotti dietetici, NAA. Parere scientifico sul livello massimo tollerabile di assunzione di vitamina d. EFSA J. 2012 , 10 , 2813. Booth, SL; Al Rajabi, A.
Determinanti dello stato della vitamina K negli esseri umani. Vitam. Horm. 2008 , 78 , 1–22.
Lanham-New, SA
Importanza di calcio, vitamina de vitamina K per la prevenzione e il trattamento dell'osteoporosi. Proc. Nutr. Soc. 2008 , 67 , 163–176. Cranenburg, CE; Vermeer, C .; Koos, R .; Boumans, ML; Hackeng, TM; Bouwman, FG; Kwaijtaal, M .; Brandeburgo, VM; Ketteler, M .; Schurgers, LJ
La forma inattiva circolante della proteina matrix gla (ucmgp) come biomarcatore per la calcificazione cardiovascolare. J. Vasc. Ris. 2008 , 45 , 427–436. Fraser, JD; Prezzo, PA
Induzione della sintesi proteica della matrice gla durante il trattamento prolungato con 1,25-diidrossivitamina d3 delle cellule di osteosarcoma. Calcif. Tissue Int. 1990 , 46 , 270-279. Seyama, Y .; Horiuch, M .; Hayashi, M .; Kanke, Y.
Effetto della vitamina k2 sulla calcinosi sperimentale indotta dalla vitamina d2 nei tessuti molli del ratto. Int. J. Vitam. Nutr. Ris. 1996 , 66 , 36-38. Braam, LA; Hoeks, AP; Brouns, F .; Hamulyak, K .; Gerichhausen, MJ; Vermeer, C.
Effetti benefici delle vitamine d e k sulle proprietà elastiche della parete dei vasi nelle donne in postmenopausa: uno studio di follow-up. Thromb. Haemost. 2004 , 91 , 373–380. Van Ballegooijen, AJ; Cepelis, A .; Visser, M .; Brouwer, IA; van Schoor, NM; Beulens, JW
Associazione congiunta di bassi livelli di vitamina D e vitamina K con pressione sanguigna e ipertensione. Ipertensione 2017 , 69 , 1165-1172. Mayer, O., Jr .; Seidlerova, J .; Wohlfahrt, P .; Filipovsky, J .; Cifkova, R .; Cerna, V .; Kucerova, A .; Pesta, M .; Fuchsova, R .; Topolcan, O .; et al.
Effetto sinergico di un basso stato di vitamina k e d sulla rigidità arteriosa in una popolazione generale. J. Nutr. Biochimica. 2017 , 46 , 83–89. Van Ballegooijen, AJ; Pilz, S .; Tomaschitz, A .; Grubler, MR; Verheyen, N.
L'interazione sinergica tra le vitamine d e k per le ossa e la salute cardiovascolare: una revisione narrativa. Int. J.
Endocrinol. 2017 , 2017 , 7454376. O'Connor, E .; Molgaard, C .; Michaelsen, KF; Jakobsen, J .; Cashman, KD
Interazione vitamina d-vitamina k: effetto della supplementazione di vitamina d sulla percentuale sierica di osteocalcina sottoarbossilata, una misura sensibile dello stato della vitamina k, nelle ragazze danesi. Br. J. Nutr. 2010 , 104 , 1091-1095.  De Koning, EJ; van Schoor, NM; Penninx, BW; Anziani, PJ; Heijboer, AC; Smit, JH; Scommetti, PM; van Tulder, MW; den Heijer, M .; van Marwijk, HW; et al.
Integrazione di vitamina D per prevenire la depressione e la scarsa funzionalità fisica negli anziani: protocollo di studio dello studio d-vitaal, uno studio clinico randomizzato controllato con placebo. BMC Geriatr. 2015 , 15 , 151. Cranenburg, CE; Schurgers, LJ; Uiterwijk, HH; Beulens, JW; Dalmeijer, GW; Westerhuis, R .; Magdeleyns, EJ; Herfs, M .; Vermeer, C .; Laverman, GD
L'assunzione e lo stato di vitamina k sono bassi nei pazienti in emodialisi. Rene Int. 2012 , 82 , 605–610. Fusaro, M .; Giannini, S .; Gallieni, M .; Noale, M .; Tripepi, G .; Rossini, M .; Messa, P .; Rigotti, P .; Pati, T .; Barbisoni, F .; et al.
L'uso di calcimimetici e analoghi della vitamina D nei pazienti emodializzati è associato a livelli aumentati di proteine dipendenti dalla vitamina K. Endocrine 2016 , 51 , 333-341. Yasui, T .; Miyatani, Y .; Tomita, J .; Yamada, M .; Uemura, H .; Miura, M .; Irahara, M.
Effetto del trattamento con vitamina k2 sulla carbossilazione dell'osteocalcina nelle prime donne in postmenopausa. Ginecol. Endocrinol. 2006 , 22 , 455–459. Arbor, NC; Darwish, HM; DeLuca, HF
Controllo trascrizionale del gene dell'osteocalcina da parte della 1,25-diidrossivitamina d-2 e del suo 24-epimero nelle cellule di osteosarcoma di ratto. Biochim. Biophys. Acta 1995 , 1263 , 147–153. Fraser, JD; Otawara, Y .; Price, PA
1,25-diidrossivitamina d3 stimola la sintesi della proteina della matrice dell'acido gamma-carbossiglutammico da parte delle cellule dell'osteosarcoma. Espressione mutuamente esclusiva di proteine ossee dipendenti dalla vitamina K da parte di linee cellulari osteoblastiche clonali. J. Biol. Chem. 1988 , 263 , 911–916. Fu, X .; Wang, XD; Mernitz, H .; Wallin, R .; Shea, MK; Booth,
L'acido retinoico SL 9-cis riduce la calcificazione renale 1alfa, 25-diidrossicolecalciferolo indotta alterando la gamma-carbossilazione dipendente dalla vitamina k della proteina dell'acido gamma-carbossiglutammico della matrice in topi maschi a / j. J. Nutr. 2008 , 138 , 2337–2341. Miyake, N .; Hoshi, K .; Sano, Y .; Kikuchi, K .; Tadano, K .; Koshihara, Y.
1,25-diidrossivitamina d3 promuove il metabolismo della vitamina k2 negli osteoblasti umani. Osteoporos. Int. 2001 , 12 , 680–687. Skeie, G .; Braaten, T .; Hjartaker, A .; Lentjes, M .; Amiano, P .; Jakszyn, P.
Uso di integratori alimentari nell'indagine prospettica europea sul cancro e studio di calibrazione nutrizionale. Euro. J. Clin. Nutr. 2009 , 63 , S226 – S238. Spiro, A .; Buttriss, JL
Vitamina d: Una panoramica dello stato e dell'assunzione di vitamina D in Europa. Nutr. Toro. 2014 , 39 , 322-350. Zittermann, A .; Ernst, JB; Prokop, S .; Fuchs, U .; Dreier, J .; Kuhn, J .; Knabbe, C .; Birschmann, I .; Schulz, U .; Berthold, HK; et al.
Effetto della vitamina D sulla mortalità per  tutte le cause nell'insufficienza cardiaca (evita): uno studio clinico randomizzato di 3 anni con 4000 UI di vitamina D al giorno. Euro. Heart J. 2017 , 38 , 2279–2286. Bolland, MJ; Grigio, A .; Avenell, A .; Gamble, GD;
Reid, integratori di calcio IR con o senza vitamina de rischio di eventi cardiovascolari: rianalisi del dataset ad accesso limitato e meta-analisi dell'iniziativa per la salute delle donne. BMJ 2011 , 342 , d2040. Thiele, I .; Linseisen, J .; Meisinger, C .; Schwab, S .; Huth, C .; Peters, A .; Perz, S .; Meitinger, T .; Kronenberg, F .; Lamina, C .; et al.
Associazioni tra uso di integratori di calcio e vitamina d, nonché le loro concentrazioni sieriche e fenotipi di malattie cardiovascolari subcliniche. Aterosclerosi 2015 , 241 , 743-751. Challoumas, D .; Stavrou, A .; Pericleous, A .; Dimitrakakis, G.
Effetti degli integratori combinati di vitamina d - calcio sul sistema cardiovascolare: dovremmo essere cauti? Aterosclerosi 2015 , 238 , 388-398. Wallace, RB; Wactawski-Wende, J .; O'Sullivan, MJ; Larson, JC; Cochrane, B .; Gass, M .; Masaki, K.
Presenza di calcoli del tratto urinario nella sperimentazione clinica randomizzata dell'iniziativa sulla salute delle donne (whi) di integratori di calcio e vitamina D. Am. J. Clin. Nutr. 2011 , 94 , 270–277. Kahwati, LC; Weber, RP; Pan, H .; Gourlay, M .; LeBlanc, E .; Coker-Schwimmer, M .; Viswanathan, M.
Vitamina d, calcio o integrazione combinata per la prevenzione primaria delle fratture negli adulti che vivono in comunità: rapporto di evidenza e revisione sistematica per la task force dei servizi di prevenzione degli Stati Uniti. JAMA 2018 , 319 , 1600-1612. Bolland, MJ; Grigio, A .; Avenell, A.
Effetti della supplementazione di vitamina D sulla salute muscolo-scheletrica: una revisione sistematica, una meta-analisi e un'analisi sequenziale di prova. Lancet Diabetes Endocrinol. 2018 , 6 , 847–858. Bjelakovic, G .; Gluud, LL; Nikolova, D .; Whitfield, K .; Wetterslev, J .; Simonetti, RG
Vitamin D supplementation for prevent of mortality in adults. Cochrane Database Syst. Rev. 2014 , 7 , CD007470. Avenell, A .; Mak, JC; O'Connell, D.
Vitamina D e analoghi della vitamina D per la prevenzione delle fratture nelle donne in post-menopausa e negli uomini più anziani. Cochrane Database Syst. Rev. 2014 , 4 , CD000227.

Food Additives, Gut Microbiota, and Irritable Bowel Syndrome: A Hidden Track

 UOC di Nutrizione Clinica, Dipartimento di Scienze Mediche e Chirurgiche, Fondazione Policlinico Universitario A. Gemelli IRCCS, Largo A. Gemelli 8, 00168 Rome, Italy
Scuola di Specializzazione in Scienza dell’Alimentazione, Università di Roma Tor Vergata, Via Montpellier 1, 00133 Rome, Italy
UOSD di Nutrizione Avanzata in Oncologia, Dipartimento di Scienze Mediche e Chirurgiche, Fondazione Policlinico Universitario A. Gemelli IRCCS, Largo A. Gemelli 8, 00168 Rome, Italy
UOC di Medicina Interna e Gastroenterologia, Dipartimento di Scienze Mediche e Chirurgiche, Fondazione Policlinico Universitario A. Gemelli IRCCS, Largo A. Gemelli 8, 00168 Rome, Italy
Dipartimento di Medicina e Chirurgia Traslazionale, Università Cattolica Del Sacro Cuore, Largo F. Vito 1, 00168 Rome, Italy
Int. J. Environ. Res. Public Health 202017(23), 8816; https://doi.org/10.3390/ijerph17238816
Received: 8 November 2020 / Revised: 23 November 2020 / Accepted: 24 November 2020 / Published: 27 November 2020

Low-grade endotoxaemia enhances artery thrombus growth via Toll-like receptor 4: implication for myocardial infarction

Roberto Carnevale, Sebastiano Sciarretta, Valentina Valenti, Flavio di Nonno, Camilla Calvieri, Cristina Nocella, Giacomo Frati, Maurizio Forte, Giulia d’Amati, Maria G Pignataro, Anna Severino, Roberto Cangemi, Alessio Arrivi, Marcello Dominici, Enrico Mangieri, Carlo Gaudio, Gaetano Tanzilli, Francesco Violi

European Heart Journal, Volume 41, Issue 33, 1 September 2020, Pages 3156–3165, https://doi.org/10.1093/eurheartj/ehz893
Published:  03 January 2020  Article history
Int J Psychophysiol. 2013 Sep;89(3):305-13.  doi: 10.1016/j.ijpsycho.2013.06.017. Epub 2013 Jun 22.

Mindfulness meditation, well-being, and heart rate variability: a preliminary investigation into the impact of intensive Vipassana meditation

Jonathan R Krygier 1James A J HeathersSara ShahrestaniMaree AbbottJames J GrossAndrew H Kemp